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Matchup rankings: Upgrade Jaylen Warren, downgrade Patrick Mahomes

By Tristan H. Cockcroft Oct 21, 2026 | 12:50 PM

The most and least favorable matchups in the NFL for this week’s games at the four key fantasy positions.

HEADLINES

Chiefs mourn Bailey after former NFL player found dead at age 37 5m ago
TE LaPorta: Will 'go get paid somewhere else' if no Lions deal 33m ago
Sources: Warriors exploring options to trade center Porzingis 33m ago
Spartans' Fears, Gators' Haugh near-unanimous picks as preseason All-Americans 1h ago
Goodell: NFL welcomes investigation into Eagles QB Hurts' medical care 1h ago

WEATHER

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